Basically, when you're on offense, it's VERY difficult for others to get away (especially in the corner). If the opponent has no DP, it's much worse. I-NO is one of THOSE characters where blocking her is the wrong option.
On the flip side, if you get pressured, you will be blocking. A LOT. Her safest and best ways to mount offense start at about half a screen away. Because of this, coupled with her climb-like dash, neutral is a bit tricky. And in bad matchups, your weaknesses (low health, below average normals, REALLY bad dizzy modifier) are multiplied. You always want your opponent on the defensive. It can be hell against characters with good neutral.
Characters like Dizzy, Slayer, Zappa, Faust, and May are nightmares.