Well clothing damage is still in and much like in IV it seems to be rather restrictive to main cast characters (in a good way) let's hope this also applies to CAS characters.
Also since the interview mentions surprises and unexpected characters I would LOVE to see ANY of the "mangaka" characters from IV return, also I would like to see Luna, Abelia, and Valeria return from III.
I wonder if we'll see anything similar to Chronicle mode, I wouldn't mind a revamped version, it was fun.