well it depends because I tend to use 5A>2B>2C or 5A>2B>3C a lot for combo's,
and yes I use 2B and the reason why because it goes into another low 5B, it goes into 2C which takes 1 primer and linkes into 4D that is a great frame trap, or I tick 360.
2B is a fucking godsend, I didn't even mention its god on block.
it really depends on what you go for, but everyone does 5A>5B>3C and have their own follow-up.