Well, for one, instead of just mixups, set up the UBs (as close as you can) and watch out for D. Learn to watch for what your opponent does and react to the things they tend to do, or yomi and such. They keep 2Ding your crossups? Delay your attacks and punish their recovery (and if they're really only using 2D, use other jumping attacks [which are overheads] till they learn or something). Throw shenanigans just not working? Well, that depends. If they keep jumpin' your throws what are you to do? Simply jump with them and air-throw . Alternatively, use 6A into air combo or air pressure (hopefully into clap). Of course, with all of these you have to predict. But this is the point. It's all about switchin' it around according to what you think they're gonna do (this goes for defense as well). With Nirvana by your side, you have a whole 'nother weapon to be feared and used, widening up your options. Basically, you wanna give them a good mind-fuck.