You're doing something funky then. 5HS will connect with everybody in the cast. If you're mid-screen, however, it's pretty much impossible to 5HS into keygrab on the heavy characters (Eddie,Robo,etc). Do like drassill said and just skip the 5HS and go straight into Keygrab in that situation.
In the corner, 5H should hit everyone and connect into keygrab. If you're in the corner you can also do c.S, f.S, 236S, 46S, 63214S, FRC, 66, 2H(2 hits) JC j.S JC j.S Keygrab.